Project Details

Type of project

• Tier 1: repurposing existing medicines
• Tier 2: testing existing molecules
• Tier 3: discovering and categorising new molecules

Therapeutic target

• Preventing infection (prophylaxis or preventing cell entry)
• Preventing virus replication in early disease
• Direct acting antiviral
• Preventing cytokine release syndrome (immunomodulation or suppression)
• Preventing death (respiratory failure, shock or multiple organ failure)

Type of supporting technology

Phase of project

• High throughput screening
• PK/PD testing and toxicology

Modality (if can be disclosed)*

• Small molecule

Molecular/cellular target (if known or can be disclosed)*

• ACE2
• SARS-CoV-2 main protease
• SARS-CoV-2 Spike protein
• NSP12, PLPro